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Optical Densitometry Study of the Newly Formed Bone Using rhBMP-2 in Wistar Rat Mandibles International Journal of Morphology
Issa,Joáo Paulo Mardegan; Nascimento,Cássio do; Sato,Sandra; Barbosa,Rodrigo Edson Santos; Benetti,Emerson Toffanello; Albuquerque Junior,Rubens Ferreira de.
The purpose of this study was to evaluate the efficacy of monoolein gel as a carrier for rhBMP-2 in the healing bone process of critical bone defects created in Wistar rats mandibles using digitalized radiographic method to analyze this process. In the group 1, the rhBMP-2 was dissolved in aqueous solution and in the group 2, the rhBMP-2 was combined with monoolein gel as a carrier. The results showed that in both of groups it was found efficient bone repair, with a great optical density in the group that the rhBMP-2 was combined with the monoolein gel, but without statistical difference between them
Tipo: Journal article Palavras-chave: Optical densitometry; RhBMP-2; Monoolein; Bone defects.
Ano: 2007 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000200018
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The Effect of Dietary Supplements on Healing of Alloplastic Bone Grafted Defects in Rat Tibia International Journal of Morphology
Kaya,A; Aktas,A; Akdemir,M. F; Kaya,B; Deveci,E.
The aim of this investigation was to evaluate the potential effects of the systemically delivered combination of calcium, zinc and vit-d supplementation of the locally applied alloplastic bone graft. 28 male Wistar albino rats were used in this study. In each animal, bone defects (10 mm length ¥ 3 mm width ¥ 2 mm depth) were created in the tibias. The animals were divided into four groups. In Group 1 (Control Group) rats were fed with standard rat diet. In Group 2 (Calcium Group) rats received calcium carbonate (15 mg/kg body weight) suspended in saline. In Group 3 (Calcium/Zinc Group) rats received calcium carbonate (15 mg/kg body weight) and zinc sulfate (4 mg/kg body weight) suspended in saline. In Group 4 (Calcium/Vitamin D Group) rats received calcium...
Tipo: Journal article Palavras-chave: Dietary supplements; Bone healing; Bone grafted; Bone defects; Tibial defects; Alloplastic bone.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000200049
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